The active substance of is the so-called essential phospholipids (EPL-substance), which are a highly purified fraction of phosphatidylcholine. The determining component of this fraction is dilinoleoylphosphatidylcholine. Essential phospholipids are similar in their chemical structure to endogenous membrane phospholipids, surpassing them in their functional properties due to their high content of polyunsaturated fatty acids, especially linoleic acid. Phospholipids are the main structural elements of cell membranes and organelle. They take part in differentiation, division and regeneration of cells.
The functional significance of phospholipids is based on their amphiphilic properties, which allows to regulate the permeability of the cell membrane. They improve the function of membranes, in particular ion exchange, the process of intracellular respiration, biological oxidation, affect the binding of intracellular respiration enzymes in the mitochondria, and also the process of oxidative phosphorylation in the energy metabolism of cells. Under physiological conditions, the synthesis of phospholipids satisfies the normal needs of hepatocytes, which contain a sufficient amount of phospholipids. It is known that the structure of cell membranes and the function of enzyme systems for liver diseases are violated. The biosynthesis of phospholipids is broken, the deficit of which leads to a disruption of the function of the cell membrane. These processes are especially pronounced in mitochondria, which are approximately 30% composed of phospholipids and the most important metabolic processes are carried out in it, including oxidative phosphorylation. With a deficiency of phospholipids, there is a disturbance in fat metabolism, which leads to fatty liver disease. Due to its pharmacological properties, Essentiale medicine eliminates these disorders, promotes the regeneration of cell membranes, reacts with broken membrane-bound enzyme systems and receptors, increases the detoxification capacity of the liver and thus normalizes its function.
Essential Forte purchase is good for use of following:
Fatty degeneration of the liver (also with diabetes);
Acute and chronic hepatitis, cirrhosis, necrosis of liver cells, hepatic coma and precoma, toxic liver damage, including toxicosis of pregnancy;
Pre- and postoperative treatment, especially for operations in the hepatobiliary zone;
The drug can be bought in various countries. Essential Forte USA is delivered in any state.
Mode of application:
Essential buy can be done in:
In the absence of other doctor’s recommendations, the initial dose is 2 capsules 3 times a day, maintenance dose is 1 capsule 3 times a day.
Take capsules while eating, without chewing, squeezed with a small amount of water.
Adults and children are prescribed intravenously slowly 5-10 ml per day, and in severe cases – 10 to 20 ml per day. At one time it is permissible to administer up to 10 ml of the drug. If the drug is administered diluted, it is recommended to use the patient’s own blood and dilute the drug in a ratio of 1: 1. Intravenous injections are usually used within 10 days. It is recommended to support (complement) parenteral therapy with capsule intake Essentiale (Essential Forte N) as soon as possible.
The general course of treatment is 3-6 months.
Treatment of psoriasis begins with 2 capsules 3 times a day for 2 weeks, after which 10 intravenous injections of 5 ml of the drug with the simultaneous appointment of PUVA-therapy.
After the termination of a course of injections the reception of a preparation inwards is renewed and continues within 2 months.
Very rarely, when taking higher doses of Essentiale, gastrointestinal upset (diarrhea) may occur.
Do not use the drug in case of hypersensitivity to any component.
The solution for intravenous administration should not be given to newborns and premature babies, since benzyl alcohol is part of this form of the drug.
Possible use during pregnancy and lactation, but only on the advice of a doctor!
Until now it is not known.
To dilute the solution for intravenous administration, electrolyte solutions should not be used.
There were no reports of overdose.
Form of issue:
Capsules forte 300 mg for 30 or 100 pieces per package.
Ampoules of 5 ml of 5 pieces per package.
Shelf life 3 years. The capsules should be stored at a temperature not exceeding 25 ° C, and ampoules at a temperature of +2 ° C to 8 ° C, in a dry place inaccessible to children.
Terms of leave from pharmacies – according to the prescription of a doctor.