Essentiale N 250 mg/ml, 5 ml (5 ampoules)

(20 customer reviews)


Manufacturer: Sanofi - Aventis

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Essentiale N 250 mg/ml (5 ampoules)

The active substance of is the so-called essential phospholipids (EPL-substance), which are a highly purified fraction of phosphatidylcholine. The determining component of this fraction is dilinoleoylphosphatidylcholine.

Essential phospholipids are similar in their chemical structure to endogenous membrane phospholipids, surpassing them in their functional properties due to their high content of polyunsaturated fatty acids, especially linoleic acid.

Phospholipids are the main structural elements of cell membranes and organelle. They take part in differentiation, division and regeneration of cells.

The functional significance of phospholipids is based on their amphiphilic properties, which allows to regulate the permeability of the cell membrane.

They improve the function of membranes, in particular ion exchange, the process of intracellular respiration, biological oxidation, affect the binding of intracellular respiration enzymes in the mitochondria, and also the process of oxidative phosphorylation in the energy metabolism of cells.

Under physiological conditions, the synthesis of phospholipids satisfies the normal needs of hepatocytes, which contain a sufficient amount of phospholipids.

It is known that the structure of cell membranes and the function of enzyme systems for liver diseases are violated. The biosynthesis of phospholipids is broken, the deficit of which leads to a disruption of the function of the cell membrane.

These processes are especially pronounced in mitochondria, which are approximately 30% composed of phospholipids and the most important metabolic processes are carried out in it, including oxidative phosphorylation. With a deficiency of phospholipids, there is a disturbance in fat metabolism, which leads to fatty liver disease.

Due to its pharmacological properties, Essentiale medicine eliminates these disorders, promotes the regeneration of cell membranes, reacts with broken membrane-bound enzyme systems and receptors, increases the detoxification capacity of the liver and thus normalizes its function.

Essentiale N purchase is good for use of following:

  • Fatty degeneration of the liver (also with diabetes);
  • Acute and chronic hepatitis, cirrhosis, necrosis of liver cells, hepatic coma and precoma, toxic liver damage, including toxicosis of pregnancy;
  • Pre- and postoperative treatment, especially for operations in the hepatobiliary zone;
  • Psoriasis, neurodermatitis;
  • Radiation syndrome.

The drug can be bought in various countries. Any state in the USA.

Mode of application:

Intravenous injections:

Adults and children are prescribed intravenously slowly 5-10 ml per day, and in severe cases – 10 to 20 ml per day. At one time it is permissible to administer up to 10 ml of the drug. If the drug is administered diluted, it is recommended to use the patient’s own blood and dilute the drug in a ratio of 1: 1. Intravenous injections are usually used within 10 days. It is recommended to support (complement) parenteral therapy with capsule intake Essentiale (Essential N) as soon as possible.

The general cycle of treatment is 3-6 months.

Treatment of psoriasis begins with 2 capsules 3 times a day for 2 weeks, after which 10 intravenous injections of 5 ml of the drug with the simultaneous appointment of PUVA-therapy.

After the termination of a course of injections the reception of a preparation inwards is renewed and continues within 2 months.

Side effects:

Very rarely, when taking higher doses of Essentiale, gastrointestinal upset (diarrhea) may occur.


Do not use the drug in case of hypersensitivity to any component.

The solution for intravenous administration should not be given to newborns and premature babies, since benzyl alcohol is part of this form of the drug.


Possible use during pregnancy and lactation, but only on the advice of a doctor!

Drug Interactions:

Until now it is not known.

To dilute the solution for intravenous administration, electrolyte solutions should not be used.


There were no reports of overdose.

Form of issue:

Ampoules of 5 ml of 5 pieces per package.

Storage conditions:

Shelf life 3 years. The capsules should be stored at a temperature not exceeding 25 ° C, and ampoules at a temperature of +2 ° C to 8 ° C, in a dry place inaccessible to children.

20 reviews for Essentiale N 250 mg/ml, 5 ml (5 ampoules)

  1. Sergey

    I started to use Essentiale in late 1996. It was hard to find it. Very effective drug.

  2. Alexandro

    Good afternoon. I am 43 years old. Never had any liver diseases. A couple of years ago I did ultrasound of the liver and the doctor said that there are some fatty liver cells and I should periodically drink preventive medication, like this one, Essentsiale.

  3. Admin

    You do not need a needle to use special nail files, it is easy to open. I used 10 ampoules intravenously … Not the greatest pleasure in my life. The effect of the drug is very good, I admitted it well, the blood tests shown improvements!

  4. Susan S.

    It helped me a lot.

  5. Geronimo

    Hey There, my package got here about three days ago! I’m very excited. Thank you so much I believe I’ll be making a big order soon.

  6. Omar

    I got six packages delivered to Austria within 9 days without any taxes to pay and without customs problems.
    The communication with the supplier is good. The shipment was done the same day I finished the payment and the tracking ID forwarded me the day after.
    Many thanks!

  7. Mindaugas

    How effective those ampoules are? Thanks in advance.

  8. Svetlana

    I always keep “Essentiale Forte” in my home medicine supply. It is composed of essential phospholipids and 6 vitamins, and it has helped me multiple times. When I was pregnant and had severe toxicosis, I received it intravenously. After 10 doses of Essentiale, my health improved greatly and my nausea was much less severe.

  9. Irene Stone

    Due to my poor health, I was prescribed Essentiale N in ampoules. Although receiving the treatment of 10 ampoules intravenously was not the most pleasant experience in my life, it was very beneficial. I found that the drug had a great effect, and it was well tolerated by me, as the results of my blood tests improved.

  10. Susan Ramos

    I found the drug to be extremely helpful in relieving me of my toxicosis. I didn’t experience any adverse side effects. My course of treatment lasted for five days and I only needed one package of the drug.

  11. Kathryn Martinez

    A year ago, my husband underwent three cycles of chemotherapy and radiation. During each treatment, he was prescribed the liver supplement Essentiale N intravenously. This was especially important due to his prior history of hepatitis making his liver an especially weak spot. Thanks to Essentiale N, his liver was able to recover and withstand the effects of both medicines and illnesses. I can confidently recommend this product to anyone!

  12. William Scott

    I had first-hand knowledge that injections of this drug were much more effective and faster than capsules. The main ingredient, phospholipids, are released directly into the liver and help to boost the organ’s vital activity and restore its normal functioning.

  13. Margaret Higgins

    I was amazed at the effectiveness of Essentiale N when I first encountered it at the maternity hospital after my child was born. My baby had a high bilirubin (jaundice) level, but the doctor suggested this medicine and it quickly worked to relieve the ailment.

  14. George Warner

    Essentiale N was created with humans in mind, so I’m going to explain its use in veterinary medicine. This drug is incredibly effective. It’s commonly used to help the liver, in combination with antibiotics, when treating animals. When administered intravenously, it quickly improves the animal’s condition. It’s a lifesaver, and the manufacturers should be thanked for that! Not only has it saved human lives, but animal lives as well.

  15. Floyd Norman

    I am taking anti-tuberculosis medications and it is not possible to restore my liver without taking a concurrent course. To help with this, I have been doing 10 injections of Essentiale N, every 3 months. I am very pleased with the results as my liver is no longer troubling me.

  16. Barbara Wright

    I find Essentiale N injections to be highly beneficial, as they are safe, effective, and have minimal side effects. They can be used to treat a variety of diseases, as well as providing hepatoprotection and helping to reduce toxicosis in expectant mothers.

  17. Grace Collins

    For the past few years, I have been living with a diagnosis of chronic cholecystitis. Despite intense pain and discomfort in my intestines, I made time to get an ultrasound of my liver and gallbladder, and subsequently visited a doctor. I was then prescribed “Essentiale N” – five intravenous injections of autoblood in a jet. The administration of the drug was painless and I experienced no side effects. After some time, a follow-up ultrasound showed that the condition of my liver had improved.

  18. Joseph Sanchez

    Last summer, I contracted food poisoning which necessitated specialized treatment. I had to receive Essentiale N injections and also took Essentiale capsules orally. After a month of this course of treatment, I was able to effectively address the issue of food poisoning and also take care of my liver.

  19. Patricia Miller

    I am pleased that this medication can be safely prescribed during pregnancy and lactation if needed. After only two days of using the product, my relative has already started to experience improvements. This particular hepatoprotective drug is often recommended by medical professionals due to its excellent value for money. It has consistently shown positive results.

  20. Charles Coleman

    Approximately two years ago, I was diagnosed with hepatitis A and prescribed Essentiale N injection solution. My doctor warned me that the recovery process of my liver would be lengthy, and I started the treatment. After two months, my indicators were back to normal and all tests confirmed this. My experience with Essentiale was not a pleasant one, but it was effective in aiding my recovery.

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